• GENOMICS
  • ANIMAL GENOMICS

Animal genomics

Genetic resources in Animal Research

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Genomics can be used to speed up the genetic improvement of livestock traits, such as milk yield, meat quality and reproductive life. The process is fairly simple: we can use DNA markers that are linked to the desired traits to identify the highest potential animals, and select those for production and breeding. This type of genomic selection has rapidly become a key strategy for breeders and producers to reduce costs and increase productivity of their herds across a range of species.

Application

  • Sequencing for SNP discovery
  • Bioinformatics to select the best SNPs for genome wide association studies
  • Identification of quantitative trait loci (QTL)
  • Build high or medium density SNP arrays to create genomic models
  • Build low density arrays and panels for marker assisted selection
  • Use diagnostic tools to identify resistant or susceptible lines

A variation in a single base (Adenine, Thymine, Cytosine or Guanine) within a sequence of DNA. SNPs do not generally cause disease directly but some SNPs may affect an individual’s susceptibility to disease or the response to the drugs and treatments.

  • Homogenous Detection
  • Microarray genotyping
  • Genome-wide selection
  • Determining genetic merit
  • Identification of QTLs
  • Comparative genetic studies
  • etc...

Quantitative trait locus (QTL) analysis is a statistical method that links two types of information—phenotypic data (trait measurements) and genotypic data (usually molecular markers)—in an attempt to explain the genetic basis of variation in complex traits. QTL analysis allows researchers in fields as diverse as agriculture, evolution, and medicine to link certain complex phenotypes to specific regions of chromosomes. The goal of this process is to identify the action, interaction, number, and precise location of these regions.

  • Singal QTL Analysis
  • Multiple QTL Analysis
  • Interval Mapping
  • Composite interval mapping
  • Family-pedigree based mapping
  • Detection of monogenic & QTL

The use of a molecular marker (e.g. DNA or RNA) linked to a trait of interest that can be used to identify the most favourable individuals to be used for breeding purposes.

  • Marker Assisted Selection
  • Genomic Wide Association Selection
  • Assessment of genetic variability and characterization of germplasm
  • Identification and fingerprinting of genotypes
  • Estimation of genetic distances between population, inbreeds, and breeding materials
  • Identification of sequences of useful candidate genes

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